Launched For Peri/Menopause product
ProVen Biotics For Peri/Menopause launched to offer a comprehensive product for women in perimenopause and menopause, that includes 50 billion of our research-backed Lab4P live bacteria with vitamins, minerals and botanicals for this stage of life.
Cultech established
Cultech was established in 1994 and quickly became internationally recognised as both an innovator and premium quality manufacturer within the nutritional supplement industry.
Lab4 probiotics introduced
Lab4 and Lab4B are lactic acid bacteria (LAB) and bifidobacteria that have been isolated from the gut microbiota of healthy humans and then screened for appropriate probiotic characteristics, ranging from resistance to stomach and bile acids, to robust capability for large-scale in vitro cultivation and commercialisation.
First Lab4 clinical trial
The first clinical study using the Lab4 friendly bacteria was the Cambridge Clostridium difficile Study. This randomised, double-blind, placebo controlled study was designed to provide evidence that supplementing with Lab4 probiotics while taking antibiotics can prevent the incidence of antibiotic associated C. difficile diarrhoea (CDAD).
ProVen Probiotics launched
After more than 10 years of research (including five major clinical trials) and having sold Lab4 probiotics to a number of major probiotics resellers around the world, Dr Nigel Plummer launches his own brand, ProVen Probiotics.
ProVen Biotics available in store
Following launch in 2012, ProVen Biotics were available to buy via independent pharmacies and health stores throughout the UK.
In-house nutritionist hired
The expansion of the ProVen brand and increase in enquiries from customers necessitated an expert to help with technical information. Adrienne Benjamin, registered Nutritional Therapist, joined the ProVen Probiotics team in November 2014.
Fit for school product launch
ProVen Biotics launched their Fit for School chewable tablets in 2014 following research using this product. The research study (known as ProChild) was published in 2015 and Fit for School stick packs were launched the same year.
ProVen launches online
ProVen Biotics was first sold online in 2015 - making the whole range and all related information available in one online space.
ProVen on sale in Boots stores
In 2016, our two best-selling products were identified by Boots as supporting their expanding digestive health section in their larger stores. ProVen Adult 25 Billion and Fit for School chewable tablets have since been available from Boots, both in-store and online.
ProVen on sale in Holland and Barrett
In 2017 two key ProVen products (Adult 25 Billion and our Child multivitamin with friendly bacteria) went on sale in more than 600 Holland & Barrett stores across the UK and Ireland. Since then, a further five products have been listed in Holland & Barrett - both online and in-store.
Four new ProVen products launched
2017 saw the launch of four brand new ProVen Biotics products to broaden the product range to 18. The new products were Women's Lactobacillus & Bifidus with Cranberry, Acidophilus & Bifidus with Digestive Enzymes, CardioPro and Adult Acidophilus & Bifidus - 50 Billion.
New manufacturing suite built
In 2018 we completed our brand new state-of-the-art probiotic production suite at our site in Port Talbot in South Wales. The facility helped us to take our live bacteria supplement manufacture and development to the next level and to ensure that we are able to continue growing into the future.
ShapeLine product launch
2020 saw the launch of our brand new ProVen Biotics ShapeLine product to rave reviews in the media. This product was developed based upon our ongoing research and includes 50 billion of our Lab4P blend of five strains of friendly bacteria (Lab4 plus Lactobacillus plantarum), combined with vitamins C and D and zinc to support immunity.
Supporting health during Covid
As the world shutdown, we ramped up production to continue to provide our supplements to all members of the family. As a critical service provider, we continued manufacture at an even greater rate than usual.

Shop the ProVen Biotics range
Scientifically formulated live bacteria products for individual life-stages and needs. Supporting gut health, immunity, and well-being for the whole family.